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    Home > Service > ริ้วรอยเหี่ยวย่น

    Line & Wrinkles correction

    What causes wrinkles?

    Wrinkles are caused from the lack of weld between Collagen A between the epidermis and dermis and Collagen B in the upper dermis or due to degradation of Elastic Fiber and Collagen C in the dermis reducing flexibility of the skin or due to the decline of water mineral and Peptide Pond in Collagen fibers fluid leading to dry and fiber deterioration.


    The problems with the skin in females during the lifetime are as follows.

    • Age 25-30 years start encountering wrinkles and slightly abnormal skin.
    • Age 30-40 years start freckled and wrinkles are more apparent especially on mouth corners skin under the eyes and around the eyes when smiling, soften facial muscles and not tighten enough.
    • Age 40-50 years more permanent wrinkles around the eyes (crow's feet) cheeks, forehead and wrinkles on the brow and flabby muscles.
    • Age 50 years and over has seborrheic keratoses and wrinkles, deeper as more sagging skin.


    1. Estrogen is a hormone reflects the unique characteristics of female in respect of the skin. It serves to accelerate the growth of skin, the epidermis and changes the collagen fibers of the dermis.  As a result, the skin is smooth and youthful.  As the age increased production of estrogen hormone is reduced, thus causing wrinkles.
    2. Postponement of the skin due to prolonged exposure to sunlight in excessive quantities, thus the resistance of the skin to sunlight is reduced. This causes dull skin, melasma, freckles and dark spots and uneven skin tone or called Photoaging.
    3. An environment with smoke, such as smoking, since nicotine in cigarettes is a molecule of free radicals which can be matched to the DNA molecules of cells that create skin tissue causing skin cells degeneration.

    How to treat wrinkles?

    Wrinkle medical treatments can be done in several ways.

    • superficial wrinkles and creases

    Using Fraxel: Restore laser is the most advanced technology in the treatment of superficial wrinkles by applying Fractioanla Photothermolysis principles use laser to stimulate the cells to generate new collagen fibers. The method is suitable for the reduction of wrinkles, hyperpigmentation or melasma, scars caused by acne and evenly toned skin.  After treatment, you can resume your daily activities as usual.

    • Wrinkles, grooves and deep creases.​
      • Botox® injection an extract from Clostridium Botulinum which allows muscles to relax. Inject Botox® at wrinkle area caused by facial muscle contractions such as eyebrows, forehead creases, crow's feet, frowned, wrinkled nose, chin and around the neck, are areas of treatment that has been very popular.

    • Hyaluronic Acid injection moisturizes and replenishes skin grooves and wrinkles leading to smooth, radiant and younger skin without wrinkles. The results can be seen immediately after treatment and has been highly appreciated today.​


    Before treatment of wrinkles, deep grooves and dark circles under the eyes

    After treatment of wrinkles, deep grooves and dark circles under the eyes


    Use care products after treatment.

    Treatment methods above are the stimulation of Fibroblast to create new collagen fibers. The creation of collagen requires additional substances.  Therefore, the application of moisturizer or serum such as Skinesia: Rapid Brightening cream or Advance night regenerating moisurizer andAll-day Revitalizing moisturizer containing Licorice, nicotinamide, Aloe vera, vitamin E,Arbutin, Vitamin C, Hyaluronic acid, ceramides, shiso, Phytospingosine help the skin creating replacement fibers faster. Wrinkles fade to make your skin younger naturally.

    For the eye area, use eye cream containing amino acids, Hyaluronic acid, Cucumber extract, Ceramides, shiso, Phytospingosine will help solve wrinkles and dark circles around the eyes better than any other substance.

    Anti-aging should begin at an early age. If you do not care now, there will be healing effect over increasing age. The dermatologist should be consulted for proper advice.

    How can we prevent aging?

    • Avoid exposure to sunlight in excessive quantities especially during 10:00 to 16:00 due to the intensity of the UV radiation is highest.
    • Use sunscreen every day despite not going outdoors because fluorescent lighting in the building also contain UVA and UVB.
    • Use skincare products that contain Anti- Aging substance available on the market such products containing Arbutin, Vitamin C, Hyaluronic acid, ceramide, shiso.
    • Avoid poses that cause facial wrinkles such as resting one's chin on one's hand, lying face down or frown.
    • Avoid smoking or cigarette smoke.

    The routine can prevent wrinkles.

    • Exercise makes skin radiant because blood is fully pumped to different parts of the body and skin.  Body gets more oxygen, allows skin cells healthy, strengthens muscles and prevents from sagging and wrinkles.
    • Good Nutrition is eating 5 groups of food in adequate to the needs of body, so that the body gets complete nutrients and vitamins. Getting healthy Results in radiant skin.
    • Stress free emotional state affects skin health because stress makes hormones in the body malfunctions, especially causing dull skin.


    Article By
    Wipanee Akarapusit M.D. (Dermatologist)

    Specialize in Dermatologic Laser and Surgery, Facial Design and Body Contouring
    MSc Dermatology, Boston, Massachusetts, USA
    Specialize in Dermatologic Laser and Surgery, Facial Design and Body Contouring
    Member of American Society for Laser Medicine and Surgery

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